Marco Fernandes MarcoFernandes

Home country: Portugal
Host institution: Institute of Cardiovascular & Medical Sciences, University of Glasgow, UK
Advisor at host institution: Dr. Holger Husi | Dr. Christian Delles
Mailing address: 126 University Place, G12 8TA, Glasgow, UK
Email address: This email address is being protected from spambots. You need JavaScript enabled to view it.

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Research interests:

My current research interest focus on the use of Systems Biology approaches, applying existing and emerging Bioinformatics tools, in order to integrate large high-throughput datasets derived from multi-omics studies. This type of studies are commonly driven by a hypothesis-free approach relying on the discovery of frequent patterns and trends in large datasets and ultimately giving a biological meaning to the information.

In the past, I was introduced to the field of Proteomics research, where I had the opportunity to put my hands on several methodologies for protein separation such as one-dimensional gel electrophoresis (1-DE) and two-dimensional gel electrophoresis (2-DE) followed by a step of identification and quantitation through mass spectrometry (MALDI TOF/TOF tandem MS) and a subsequent step of validation using Western blotting. I also used an alternative methodology to label-free approaches, such as the isobaric tags for relative and absolute quantitation (iTRAQ), which as the advantage of enabling the simultaneous analysis of up-to 8 samples in just one run and thus removing the bias associated with sample complexity and independent runs.

 

 

 


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